PROCESS FOR PROTEIN REFOLDING BY MEANS OF BUFFER EXCHANGE USING A CONTINUOUS STATIONARY PHASE CAPABLE OF SEPARATING PROTEINS FROM SALT

Disclosed is a quick and efficient refolding process which utilizes cellulos ic rolled stationary phase to rapidly separate the reduced, denatured protein from the denaturant solution, thereby promoting high protein refold yields a t higher protein concentrations, while significantly decreasing the...

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Bibliographic Details
Main Authors SEELY, ROBERT J, LADISCH, MICHAEL R
Format Patent
LanguageEnglish
French
Published 25.09.2001
Edition6
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Disclosed is a quick and efficient refolding process which utilizes cellulos ic rolled stationary phase to rapidly separate the reduced, denatured protein from the denaturant solution, thereby promoting high protein refold yields a t higher protein concentrations, while significantly decreasing the volume needed to achieve protein refolding.
Bibliography:Application Number: CA19962227318