CALCIUM CHANNEL ANTAGONISTS

A method for antagonizing or blocking calcium channels in vascular tissue, comprising administering to an animal in need thereof a pharmaceuticallyeffective amount of a compound having formula (I) wherein R1 and R3 are independently hydrogen, C1-C4 alkyl, -CO-(C1-C6 alkyl), or -CH2Ar, -CO-Ar, wherei...

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Bibliographic Details
Main Author COHEN, MARLENE LOIS
Format Patent
LanguageEnglish
French
Published 19.12.1996
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A method for antagonizing or blocking calcium channels in vascular tissue, comprising administering to an animal in need thereof a pharmaceuticallyeffective amount of a compound having formula (I) wherein R1 and R3 are independently hydrogen, C1-C4 alkyl, -CO-(C1-C6 alkyl), or -CH2Ar, -CO-Ar, wherein Ar is phenyl or substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically-acceptable salt thereof.
Bibliography:Application Number: CA19962223711