PROCESS FOR THE PREPARATION OF AN HIV PROTEASE INHIBITING COMPOUND

Processes are disclosed for the preparation of (2S, 3S, 5S)-5-(N-(N-((N-Methyl-N-((2-isopropyl-4- thiazolyl)methyl)amino)carbonyl)--L-valinyl)amino)-2-(N-((5- thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane or an acid addition salt thereof and (2S, 3S, 5S)-5-(N-(N-((N-Methyl-N-((2-isop...

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Bibliographic Details
Main Authors MENZIA, JEROME A, COOPER, ARTHUR J, TIEN, JIEN-HEH
Format Patent
LanguageEnglish
French
Published 18.09.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Processes are disclosed for the preparation of (2S, 3S, 5S)-5-(N-(N-((N-Methyl-N-((2-isopropyl-4- thiazolyl)methyl)amino)carbonyl)--L-valinyl)amino)-2-(N-((5- thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane or an acid addition salt thereof and (2S, 3S, 5S)-5-(N-(N-((N-Methyl-N-((2-isopropyl-4thiazolyl)methyl)amino)carbonyl)-D- valinyl)amino)-2-(N-((5-thiazolyl)methoxycarbonyl)amino- 1,6-diphenyl-3-hydroxyhexane or an acid addition salt thereof.
Bibliography:Application Number: CA19962219983