PROTEASE-CONTAINING CLEANING COMPOSITIONS

• Main Authors: BAECK, ANDRE, BARNETT, BOBBY LEE, GHOSH, CHANCHAL KUMAR, GRAYCAR, THOMAS PAUL, BRODE, PHILIP FREDERICK, III, RUBINGH, DONN NELTON, WILSON, LORI JEAN, BOTT, RICHARD RAY
• Format: Patent
• Language: English; French
• Published: 27.05.2003
• Edition: 6
• Subjects: ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES; BEER; BIOCHEMISTRY; CALCULATING; CANDLES; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; COMPUTING; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; COUNTING; CULTURE MEDIA; DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FORADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORYOR FORECASTING PURPOSES; DETERGENT COMPOSITIONS; DETERGENTS; ENZYMOLOGY; FATTY ACIDS THEREFROM; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; RECOVERY OF GLYCEROL; RESIN SOAPS; SOAP OR SOAP-MAKING; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; SPIRITS; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE,COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTINGPURPOSES, NOT OTHERWISE PROVIDED FOR; USE OF SINGLE SUBSTANCES AS DETERGENTS; VINEGAR; WINE

The present invention relates to cleaning compositions comprising protease e nzyme which is a carbonyl hydrolase variant having an amino acid sequence not found in nature, which is derived by replacement of a plurality of amino acid residues of a precursor carbon yl hydrolase with different amino acids, wherein said plurality of amino acid r esidues replaced in the precursor enzyme correspond to p osition +76 in combination with one or more of the following residues: +99, +101, +1 03, +104, +107, +123, +27, +105, +109, +126, +128, +135, +156, +166, +195, +197, +204, +206, +210, +216, +217, +218, +222, +260, +265 , and/or +274, where the numbered positions correspond to naturally-occurring subtilisin from Bacillus amyloliquefaciens or to equival ent amino acid residues in other carbonyl hydrolase or s ubtilisins (such as Bacillus lentus subtilisin).