IMMUNOMODULATOR CELL ADHESION INHIBITOR, AND AGENT FOR TREATING AND PREVENTING AUTOIMMUNE DISEASES

A 4H-I-benzopyran-4-one derivative of general formula (1), (see formula 1) or a salt thereof exerts excellent effects of immunomodulation and cell adhesion inhibition, and is further expected to have the effect of relieving autoimmune diseases at a level comparable to that of steroids. Thus the comp...

Full description

Saved in:
Bibliographic Details
Main Authors TAKANO, SHUNTARO, SHIMOTORI, TOMOYA, AIKAWA, YUKIHIKO, TANAKA, KEIICHI, INABA, TAKIHIRO, MAKINO, SHINJI, OSHIO, ICHIRO, YOSHIDA, CHOSAKU, TANIGUCHI, YOICHI
Format Patent
LanguageEnglish
French
Published 25.07.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:A 4H-I-benzopyran-4-one derivative of general formula (1), (see formula 1) or a salt thereof exerts excellent effects of immunomodulation and cell adhesion inhibition, and is further expected to have the effect of relieving autoimmune diseases at a level comparable to that of steroids. Thus the compound of general formula (1) is useful in the treatment and prevention of autoimmune diseases fundamentally caused by immunopathy or abnormally accelerated cell adhesion, for example, chronic rheumatoid arthritis, systemic lupus, erythematosus, sclerema, mixed connective tissue disease, polyarteritis nodosa, polymyositis/dermatomyositis, Sjogren's syndrome, Behcet's disease, multiple sclerosis, autoimmune diabetes, Hashimoto's disease, psoriasis, primary myxedema, pernicious anemia, serious adynamia, ulcerative colitis, chronic active hepatitis, autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura.
Bibliography:Application Number: CA19942159192