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A compound of formula (I), where E is oxygen or sulphur, A is CR3 or N where R3 is hydrogen or hydrocarbyl; D (see fig. I) completes a 5 or 6-membered non-aromatic heterocyclic ring which optionally contains additional heteroatoms selected from oxygen nitrogen or sulpur and which is optionally subst...

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Main Authors COLLINS, DAVID JOHN, BARNES, NIGEL JOHN, BARTON, JOHN EDWARD DUNCAN, MITCHELL, GLYNN, SHRIBBS, JOHN MARTIN, KOWALCZYK, BOGDAN, KAY, IAN TREVOR, COX, JOHN MICHAEL, SMITH, STEPHEN CHRISTOPHER
Format Patent
LanguageEnglish
French
Published 23.06.1994
Edition6
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Summary:A compound of formula (I), where E is oxygen or sulphur, A is CR3 or N where R3 is hydrogen or hydrocarbyl; D (see fig. I) completes a 5 or 6-membered non-aromatic heterocyclic ring which optionally contains additional heteroatoms selected from oxygen nitrogen or sulpur and which is optionally substituted by an optionally substitu ted lower hydrocarbyl group, or an optionally substituted heteroaryl group; R1 and R2 are each independently hydrogen, optionally substitu ted lower hydrocarbyl or optionally substituted heteroaryl, or R1 and R2 together with the nitrogen atom to which they are attached form a h eterocyclic ring; Z represents halogen, optionally substituted lower hydrocarbyl, optionally substituted lower hydrocarbyloxy, opti onally substituted lower hydrocarbylthio, hydrocarbylsulphinyl, or hydrocarbylsulphonyl cyano, nitro, CHO, NHOH, ONR7'R7", SF5, CO (optionally s ubstituted lower hydrocarbyl), acylamino, COOR7. SO2NR8R9, CONR10R11, OR12 or NR13R14 where R7, R7', R7", R8, R9, R10 and R11 are independently H or lower hydrocarbyl; R12 is hydrogen, SO2 lower hydrocarbyl or COR15; R13 and R14 are independently lower hy drocarbyl, lower hydrocarbyloxy or a group R12; R15 is OR16, NR17R18, hydrogen or lower hydrocarbyl; R16 is lower hydrocarbyl, R17 a nd R18 are independently hydrogen or lower hydrocarbyl provided that when there are two or more substituents Z, they may be the same or different; and m is 0 or an integer from 1 to 5.
Bibliography:Application Number: CA19932149530