CYCLOPEPTIDES OF THE FORMULA I

The invention relates to novel cyclopeptides of the formula I cyclo-(Arg-A-Asp-R1-R2) I in which A, R1 and R2 have the meaning given in Claim 1, and their salts. These compounds act as integrin inhibitors and can be used in particular for the prophylaxis and treatment of disorders of the circulation...

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Bibliographic Details
Main Authors KESSLER, HORST, JONCZYK, ALFRED, HOLZEMANN, GUNTER, GOODMAN, SIMON, WERMUTH, JOCHEN, HAUBNER, ROLAND
Format Patent
LanguageEnglish
French
Published 10.04.2007
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to novel cyclopeptides of the formula I cyclo-(Arg-A-Asp-R1-R2) I in which A, R1 and R2 have the meaning given in Claim 1, and their salts. These compounds act as integrin inhibitors and can be used in particular for the prophylaxis and treatment of disorders of the circulation, bones and in tumour therapy, and as antimicrobial and antiviral active compounds.
Bibliography:Application Number: CA19952148194