FLUORINATED VITAMIN D3 DERIVATIVE

This invention is for 1.alpha.-fluoro-25-hydroxy-16-ene-23-yne- cholecalciferol, which can be further characterized by the formula: and which is useful as an agent for the treatment of sebaceous gland diseases such as acne and sebhorreic dermatitis. It can be prepared by removing the silyl protectin...

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Bibliographic Details
Main Authors USKOKOVIC, MILAN RADOJE, SHIUEY, SHIAN-JAN, DORAN, THOMAS I
Format Patent
LanguageEnglish
French
Published 09.05.2006
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention is for 1.alpha.-fluoro-25-hydroxy-16-ene-23-yne- cholecalciferol, which can be further characterized by the formula: and which is useful as an agent for the treatment of sebaceous gland diseases such as acne and sebhorreic dermatitis. It can be prepared by removing the silyl protecting groups from a corresponding compound with silyl protected hydroxy groups.
Bibliography:Application Number: CA19952141652