METHOD FOR MAKING A PRECONJUGATE

2130170 9416330 PCTABS00033 A method for making a preconjugate comprising an immunogenic species of a polymorphic analyte is disclosed. The method is carried out by reacting an activated binding moiety, and a polymorphic analyte at room temperature for between about 10 hours and about 60 hours. The...

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Bibliographic Details
Main Authors OH, CHAN S, CHENG, ANTHONY K, DOBASHI, THOMAS S, MICHAEL, JOSEPHINE M
Format Patent
LanguageEnglish
French
Published 21.07.1994
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
TESTING
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Summary:2130170 9416330 PCTABS00033 A method for making a preconjugate comprising an immunogenic species of a polymorphic analyte is disclosed. The method is carried out by reacting an activated binding moiety, and a polymorphic analyte at room temperature for between about 10 hours and about 60 hours. The attaching reaction results in an excess of the preconjugate comprising the immunogenic species of the polymorphic analyte. The preconjugate can be used to make an immunoreactive conjugate useful as a developer antigen in a competitive inhibition immunoassay for the polymorphic analyte.
Bibliography:Application Number: CA19932130170