PROCESS FOR PREPARING 2-AMINO-3-HYDROXY ACIDS

The invention provides a process for preparing 2-amino-3-hydroxy acids. The process comprises mixing an aldehyde, and glycine with Escherichia coli serine hydroxymethyltransferase in the presence of pyridoxal 5'-phosphate to form the corresponding L-erythro-2-amino-3-hydroxy acid.

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Bibliographic Details
Main Authors KROEFF, EUGENE P, ZOCK, JOSEPH M, DOTZLAF, JOE E, QUEENER, STEPHEN W, GAZAK, ROBERT J, YEH, WU-KUANG, KREUZMAN, ADAM J, VICENZI, JEFFREY T
Format Patent
LanguageEnglish
French
Published 26.11.1994
Edition5
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention provides a process for preparing 2-amino-3-hydroxy acids. The process comprises mixing an aldehyde, and glycine with Escherichia coli serine hydroxymethyltransferase in the presence of pyridoxal 5'-phosphate to form the corresponding L-erythro-2-amino-3-hydroxy acid.
Bibliography:Application Number: CA19942124171