ANTITHROMBIN COMPOSITION AND PROCESS FOR PREPARATION THEREOF

An antithrombin composition in the form of a lipid emulsion which comprises, together with unsaturated fatty acid and an emulsifier, N2-arylsulfonyl-L-arginineamide of the following general formula (I): ... (I) wherein R1 represents (2R,4R)-4-alkyl-2-carboxypiperidino group, R2 represents phenyl gro...

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Bibliographic Details
Main Author IGAKI, MATSUO
Format Patent
LanguageEnglish
French
Published 26.07.1994
Edition5
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:An antithrombin composition in the form of a lipid emulsion which comprises, together with unsaturated fatty acid and an emulsifier, N2-arylsulfonyl-L-arginineamide of the following general formula (I): ... (I) wherein R1 represents (2R,4R)-4-alkyl-2-carboxypiperidino group, R2 represents phenyl group or condensed polycyclic compound residue as defined below, said R2 optionally having one or more substituents selected from lower alkyl group, lower alkoxy group, or amino group substituted by lower alkyl group, said condensed polycyclic compound residue being a condensed polycyclic compound residue including a benzene ring, said benzene ring being bound to the sulfur atom of the sulfonyl group in the general formula (I), and said benzene ring being condensed with other ring which may be a heterocyclic ring, and said polycyclic compound residue having 7 - 14 carbon atoms in total, its hydrate and/or its salt is provided.
Bibliography:Application Number: CA19942114153