QUATERNARY AMMONIUM SALTS DERIVED FROM CHITOSAN

Quaternary ammonium salts of chitosan possessing hypocholesterolemic activity of formula (II) in which A represents the monomer unit of a chitosan, m is a whole number between 100 and 1,000. R1 is C1-C4 linear alkyl and Xn- is a physiologically acceptable water soluble polyanion, where n is at least...

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Bibliographic Details
Main Authors CURATOLO, WILLIAM JOHN, CHANDLER, CHARLES EDWARD
Format Patent
LanguageEnglish
French
Published 27.01.1998
Edition6
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Summary:Quaternary ammonium salts of chitosan possessing hypocholesterolemic activity of formula (II) in which A represents the monomer unit of a chitosan, m is a whole number between 100 and 1,000. R1 is C1-C4 linear alkyl and Xn- is a physiologically acceptable water soluble polyanion, where n is at least 10 but not greater than about 10,000, and any remaining positive charges are balanced by nonpolymeric anions.
Bibliography:Application Number: CA19912092401