WATER SOLUBLE CAMPTOTHECIN ANALOGUES, PROCESSES AND METHODS

A process for the preparation of water soluble camptothecin analogs of Formu la (Ib), including methods for the preparation of intermediates thereof, and the compounds prepared by said process. Water soluble camptothecin analogs are prepared which may be used for inhibiting the growth of tumor cells...

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Bibliographic Details
Main Authors WOOD, JEFFERY L, MASTROCOLA, ANTONIETTA R, FORTUNAK, JOSEPH M, MELLINGER, MARK, BURK, PATRICK L
Format Patent
LanguageEnglish
French
Published 06.02.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A process for the preparation of water soluble camptothecin analogs of Formu la (Ib), including methods for the preparation of intermediates thereof, and the compounds prepared by said process. Water soluble camptothecin analogs are prepared which may be used for inhibiting the growth of tumor cells sensitive to such analogs.
Bibliography:Application Number: CA19912090967