[3H,7H]THIAZOLO[3,4-A]PYRIDINES WITH ANTIASTHMATIC AND A ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT

Compounds of formula (I) wherein R is an alkyl group; R1 is a cyano carboxy, alkoxycarbonyl, aminocarbonyl or hy- droxylaminocarbonyl group; R2 is substituted or unsubstituted phenyl, (C3-C7 )- cycloalkyl, .alpha.-, .beta.- or .gamma.-pyridyl or a benzohe- terocyclic ring; R3 is carboxy or carboalko...

Full description

Saved in:
Bibliographic Details
Main Authors GALLICO, LICIA, DE CILLIS, GIAMPIERO, GANDOLFI, CARMELO A, LONG, GIORGIO
Format Patent
LanguageEnglish
French
Published 30.10.2001
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Compounds of formula (I) wherein R is an alkyl group; R1 is a cyano carboxy, alkoxycarbonyl, aminocarbonyl or hy- droxylaminocarbonyl group; R2 is substituted or unsubstituted phenyl, (C3-C7 )- cycloalkyl, .alpha.-, .beta.- or .gamma.-pyridyl or a benzohe- terocyclic ring; R3 is carboxy or carboalkoxy; Y is a group of the formula COOX; -NHCOA; -NCO; -COA; -CONHOR e; -OCOA; A; -CO-CH2-CO-R f; -NHCSA; -OCSA; (a); X is hydrogen, alkyl or a succinimidyl group; A is a cyclic of acyclic amino group; and n is 1 or 2; having pharmacological characteristics which render them useful in the treatment of inflam- matory conditions of the respiratory tract and asthmatic conditions.
Bibliography:Application Number: CA19912084669