ACID-LABILE LINKER MOLECULES
. This invention relates to the field of immune therapy of cancer, more specifically to immunoconjugates of a cytotoxic moiety with a targeting moiety, more specifically to immunoconjugates of antibodies or fragments or functional derivatives of antibodies coupled to a cytotoxic substance such as dr...
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Main Authors | , , |
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Format | Patent |
Language | English French |
Published |
01.07.1992
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | . This invention relates to the field of immune therapy of cancer, more specifically to immunoconjugates of a cytotoxic moiety with a targeting moiety, more specifically to immunoconjugates of antibodies or fragments or functional derivatives of antibodies coupled to a cytotoxic substance such as drugs, toxins or radioisotopes. It especially relates to the release of substances bound to a targeting moiety through the use of acid-cleavable linker molecules. |
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Bibliography: | Application Number: CA19912058595 |