Controlled Release Pharmaceutical Preparation and Method fo r Producing the Same

A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and slightly water-permeable acrylic polymer containing a trimeth...

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Main Authors NODA, KAZUO, HIRAKAWA, YOSHIYUKI, YOSHINO, HIROYUKI, NARISAWA, SHINJI
Format Patent
LanguageEnglish
French
Published 29.06.1991
Edition5
Subjects
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Abstract A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and slightly water-permeable acrylic polymer containing a trimethylammonium-ethyl group, which exhibits well controlled dissolution and release of the pharmaceutically active substance when administered and can maintain the desired blood level of the active substance for a long period of time, and a method for producing the preparation.
AbstractList A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and slightly water-permeable acrylic polymer containing a trimethylammonium-ethyl group, which exhibits well controlled dissolution and release of the pharmaceutically active substance when administered and can maintain the desired blood level of the active substance for a long period of time, and a method for producing the preparation.
Author HIRAKAWA, YOSHIYUKI
NODA, KAZUO
YOSHINO, HIROYUKI
NARISAWA, SHINJI
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DocumentTitleAlternate Préparation pharmaceutique à libération contrôlée et procédé de fabrication de ladite préparation
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Snippet A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Controlled Release Pharmaceutical Preparation and Method fo r Producing the Same
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