Controlled Release Pharmaceutical Preparation and Method fo r Producing the Same

A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and slightly water-permeable acrylic polymer containing a trimeth...

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Bibliographic Details
Main Authors NODA, KAZUO, HIRAKAWA, YOSHIYUKI, YOSHINO, HIROYUKI, NARISAWA, SHINJI
Format Patent
LanguageEnglish
French
Published 29.06.1991
Edition5
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and slightly water-permeable acrylic polymer containing a trimethylammonium-ethyl group, which exhibits well controlled dissolution and release of the pharmaceutically active substance when administered and can maintain the desired blood level of the active substance for a long period of time, and a method for producing the preparation.
Bibliography:Application Number: CA19902033277