4-(2-METHYL-2-HYDROXYPROPYLAMINO)-5,6-DIHYDROTHIENO-[2,3-B] THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE

10/WHN4 17906 TITLE OF THE INVENTION 4-(2-METHYL-2-HYDROXYPROPYLAMINO)-5,6-DIHYDROTHIENO-¢2,3-B!THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE 4-(2-Methyl-2-hydroxypropylamino)-5,6-dihy-drothieno¢2,3-b!thiopyran-2-sulfonamide-7,7-dioxide is a major mammalian metabolite of 4-(2-methylpropyl-amino)-5,6-dihydroth...

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Bibliographic Details
Main Authors ZACCHEI, ANTHONY G, LEE, LING L, VARGA, SANDOR L, HOFFMAN, JACOB M., JR
Format Patent
LanguageEnglish
French
Published 01.02.1991
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:10/WHN4 17906 TITLE OF THE INVENTION 4-(2-METHYL-2-HYDROXYPROPYLAMINO)-5,6-DIHYDROTHIENO-¢2,3-B!THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE 4-(2-Methyl-2-hydroxypropylamino)-5,6-dihy-drothieno¢2,3-b!thiopyran-2-sulfonamide-7,7-dioxide is a major mammalian metabolite of 4-(2-methylpropyl-amino)-5,6-dihydrothieno¢2,3-b!thiopyran-2-sulfon-amide-7,7-dioxide and is itself an active carbonic anhydrase inhibitor useful in the treatment of ocular hypertension by topical administration.
Bibliography:Application Number: CA19902022118