OPTICALLY ACTIVE NAPHTHYLETHANOL DERIVATIVE

An optically active naphthylethanol compound, or a pharmacologically acceptable salt thereof, useful in the pharmacological field for the treatment, prevention and cure of mental symptoms associated with cerebral vascular disorders, and defined by the following formula is disclosed: Particularly use...

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Bibliographic Details
Main Authors KARIBE, NORIO, SUGIMOTO, HACHIRO, KANEKO, TAKERU, YAMATSU, KIYOMI, UENO, MASATAKA, NAKAZAWA, TAKAHIRO
Format Patent
LanguageEnglish
French
Published 20.01.1991
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:An optically active naphthylethanol compound, or a pharmacologically acceptable salt thereof, useful in the pharmacological field for the treatment, prevention and cure of mental symptoms associated with cerebral vascular disorders, and defined by the following formula is disclosed: Particularly useful are two derivatives of the above compound, namely (S)-(+)-2-¢4-(p-fluorobenzoyl)-1-piperidyl!-l-naphthylethanol and (R)-(-)-2-¢4-(p-fluorobenzoyl)-l-piperidyl!-l-naphthylethanol.
Bibliography:Application Number: CA19902021154