CYCLOALKYLAMIDES OF (8B)-1ALKYL-6 (SUBSTITUTED)ERGOLINES

This invention provides (8.beta.)-N-cycloalkyl-1-alkyl-6-(substituted)ergoline-8-carboxamides useful for blocking 5HT2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm,...

Full description

Saved in:
Bibliographic Details
Main Authors MARZONI, GIFFORD PURNELL, FOREMAN, MARK MORTENSEN, WHITTEN, KATHLEEN ROSE, GARBRECHT, WILLIAM LEE
Format Patent
LanguageEnglish
French
Published 10.02.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:This invention provides (8.beta.)-N-cycloalkyl-1-alkyl-6-(substituted)ergoline-8-carboxamides useful for blocking 5HT2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, thrombosis, ischemia, depression, anxiety, sleep disorders and appetite disorders with a compound of the invention.
Bibliography:Application Number: CA19880569291