PROCESS FOR THE PREPARATION OF HIGHLY STABLE, SOFT GELATINE CAPSULES FOR THERAPEUTICAL PURPOSES

• Main Authors: BACSA, GYORGY, GOMBOS, ZOLTAN, JANCSO, SANDOR, EMRI, ZSUZSANNA NEE HARSY, VAGO, GYORGY, SZABO, ERZSEBET, ZAMBO, ISTVAN, DANOS, BELA, TETENYI, PETER, KAPOSI, PAL
• Format: Patent
• Language: English; French
• Published: 20.12.1994
• Edition: 5
• Subjects: EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKINGOILS; FOODS OR FOODSTUFFS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The invention relates to a process for the preparation of therapeutically useful, highly stable soft gelatine capsules containing naturally occurring oils obtained by the cold pressing of mainly plant parts (seeds), which comprises adjusting the free fatty acid content of the oil to a value according to an acid number of 0.3 to 4.5 by mixing oils of identical or different natural source with a different composition (acid number) characterized by an acid number of at most 4.5 and then filling the oil in a manner known in se into soft gelatine capsules optionally aromatized by 1 to 10% by mass of a synthetic flavouring agent. The capsules thus obtained have a resistant double wall consisting of gelatine as an outer layer and of a complex as inner layer which is formed from the free fatty acid content of the plant oils and the gelatine.