N-PHENYL BUTENAMIDES WITH PHARMACEUTICAL PROPERTIES
N-PHENYL BUTENMIDES WITH PHARMACEUTICAL PROPERTIES Compounds of the following formula have pharmaceutical properties: (I) in which X is R1(HO)C=C(CN)-, R1(CO)-CH(CN)- or R1 and R2 are each hydrogen or C1-6 alkyl, R3, R4 and R5 are each hydrogen, hydroxy, halogen, nitro, cyano, carboxy, C1-4 alkyl, C...
Saved in:
Main Authors | , , |
---|---|
Format | Patent |
Language | English French |
Published |
18.05.1993
|
Edition | 5 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | N-PHENYL BUTENMIDES WITH PHARMACEUTICAL PROPERTIES Compounds of the following formula have pharmaceutical properties: (I) in which X is R1(HO)C=C(CN)-, R1(CO)-CH(CN)- or R1 and R2 are each hydrogen or C1-6 alkyl, R3, R4 and R5 are each hydrogen, hydroxy, halogen, nitro, cyano, carboxy, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, halo-substituted C1-4 alkyl, halo-substituted C1-4 alkoxy, halo-substituted C1-4 alkylthio, C2-5 alkoxycarbonyl, optionally substituted phenyl, optionally substituted phenoxy, R'R"N- where R' and R" are each hydrogen or C1-4 alkyl R'''CONH- where R''' is C1-4 alkyl, R6, R7 and R8 are each C1-6 alkyl, halo-substituted C1-6 alkyl or optionally substituted phenyl, or R6 and R7, together with the carbon atom to which they are attached, form a cycloalkyl group containing 3 to 7 carbon atoms, or R6, R7 and R8 together with the carbon atom to which they are attached, form a bicycloalkyl group containing 4 to 9 carbon atoms; and salts thereof. |
---|---|
Bibliography: | Application Number: CA19870543739 |