SULFONYLUREA DERIVATIVES

This invention provides sulfonamide derivatives of formula (I): (I) in which A is -O-, ?CH3, -CH2-, -CH2CH2-, or -CH2O-; D is -CH2- or -O-; provided that neither A nor D can be -O- unless both A and D are -O-; R1 is hydrogen or halo, and R2 is halo or trifluoromethyl. These derivatives are useful in...

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Bibliographic Details
Main Authors RIEDER, BRENT J, TAO, EDDIE V.P, AIKINS, JAMES A, HOWBERT, JAMES J, HARPER, RICHARD W, POORE, GERALD A
Format Patent
LanguageEnglish
French
Published 12.03.1991
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:This invention provides sulfonamide derivatives of formula (I): (I) in which A is -O-, ?CH3, -CH2-, -CH2CH2-, or -CH2O-; D is -CH2- or -O-; provided that neither A nor D can be -O- unless both A and D are -O-; R1 is hydrogen or halo, and R2 is halo or trifluoromethyl. These derivatives are useful in the treatment of susceptible neoplasms in warm-blooded animals.
Bibliography:Application Number: CA19860518656