OXIDATION OF 2-ARYLPROPANALS

ABSTRACT OF THE DISCLOSURE 2-(4-isobutylphenol) propionic acld (*ibuprofen and other 2-aryl propionic acids useful as analgesic and anti-inflammatory agents, are produced by oxidation of the corresponding 2-aryl propionaldehydes with oxygen in the presence of soluble manganese or cobalt catalysts, w...

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Bibliographic Details
Main Authors RILEY, DENNIS P, GETMAN, DANIEL P, BECK, GARY R
Format Patent
LanguageEnglish
French
Published 14.08.1990
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
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Summary:ABSTRACT OF THE DISCLOSURE 2-(4-isobutylphenol) propionic acld (*ibuprofen and other 2-aryl propionic acids useful as analgesic and anti-inflammatory agents, are produced by oxidation of the corresponding 2-aryl propionaldehydes with oxygen in the presence of soluble manganese or cobalt catalysts, with high selectivities with soluble manganese salts, or with soluble cobalt salts along with sodium salts. *Trademark
Bibliography:Application Number: CA19860523680