PYRIDINE COMPOUNDS WITH BASIC SUBSTITUENTS, A PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, AND THEIR USE

HOE 85/F 259 : A process for the manufacture of a pyridine compound of the formula I (I) in which R1 and R2 independently of each other represent hydrogen or alkyl having from 1 to 4 carbon atoms, R3 represents hydrogen or alkyl having up to 2 carbon atoms and A represents alkylene having 2 to 4 car...

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Bibliographic Details
Main Authors ANAGNOSTOPULOS, HIRISTO, BARTLETT, ROBERT R, ELBEN, ULRICH
Format Patent
LanguageEnglish
French
Published 04.07.1989
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:HOE 85/F 259 : A process for the manufacture of a pyridine compound of the formula I (I) in which R1 and R2 independently of each other represent hydrogen or alkyl having from 1 to 4 carbon atoms, R3 represents hydrogen or alkyl having up to 2 carbon atoms and A represents alkylene having 2 to 4 carbon atoms, n is 0 or 1, Z is a group of the formula Za, Zb or Zc (Za) (Zb) (Zc) in which either R4 is hydrogen and R5 is phenyl or cinnamyl or R4, R5, R7 and R8 independently of each other are pyridyl, phenyl or phenyl which is substituted by up to 2 equal or different substituents from the group halogen and alkoxy having up to 2 carbon atoms, R6 is hydrogen or hydroxy and X is hydrogen, a cyano, amino or nitro group or the group -CO-R9, in which R9 is hydroxy or alkoxy having from 1 to 4 carbon atoms, and of the physiologically tolerable salts of these compounds,
Bibliography:Application Number: CA19860523703