SALTS OF OXAZAPHOSPHORINE DERIVATIVES AND THEIR PREPARATION

There are provided new antitumor salts of oxazaphosphorine derivatives of the formula: in which A is the group -S-alk-S03H and alk represents a C2-C6-alkylene residue with a basic compound of the formula: II wherein R4 is a hydroxy group or an amino group, R6 is hydrogen a C1-C6-alkyl group or a C1-...

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Bibliographic Details
Main Authors NIEMEYER, ULF, HILGARD, PETER, POHL, JOERG, ENGEL, JURGEN, KLEEMANN, AXEL
Format Patent
LanguageEnglish
French
Published 30.05.1989
Edition4
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:There are provided new antitumor salts of oxazaphosphorine derivatives of the formula: in which A is the group -S-alk-S03H and alk represents a C2-C6-alkylene residue with a basic compound of the formula: II wherein R4 is a hydroxy group or an amino group, R6 is hydrogen a C1-C6-alkyl group or a C1-C6-alkyl group which is substituted by an amino group, or a guanidino group.
Bibliography:Application Number: CA19850475401