SYNTHETIC COPOLYMER SURGICAL ARTICLES AND METHOD OF MANUFACTURING THE SAME

• Main Authors: CASEY, DONALD J, ROBY, MARK S
• Format: Patent
• Language: English; French
• Published: 20.05.1986
• Edition: 4
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; THEIR PREPARATION OR CHEMICAL WORKING-UP

SYNTHETIC COPOLYMER SURGICAL ARTICLES AND METHOD OF MANUFACTURING THE SAME A triblock copolymer having a proportion of units having the formula: < IMG > (I) as the end blocks, said formula I as an end block having a hydrogen atom attached to the terminal oxygen atom, and the formula (I) randomly combined with a proportion of units having the formula: < IMG > (II) as the middle block finds particular advantageous use in manufacturing absorbable monofilament sutures and other surgical articles. A surgical article is manufactured from a synthetic absorbable copolymer formed by copolymerizing glycolide with 1,3- dioxan-2-one (trimethylene carbonate) wherein a combination of the monomers is substantially completely polymerized before the addition of the other monomer in the presence of a difunctional initiator at or below about 180.degree.C; glycolide is added and the temperature increased up to about the melting point of poly glycolide to form a triblock copolymer with a proportion of units having the formula: < IMG > as the end blocks, and the formula (I) randomly combined with a proportion of units having the formula: < IMG > (II) as the middle block.