NITROSAMINE-FREE 3-ISOTHIAZOLONES AND PROCESS

• Main Authors: BAYER, HORST O, PETIGARA, RAMESH B, LANGE, BARRY C
• Format: Patent
• Language: English; French
• Published: 25.06.1985
• Edition: 4
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; TRAPPING

Disclosed herein are biocidal concentrate compositions suitable for applications where substantial human or animal contact is anticipated; and also their method of use and process of preparation. The compositions comprise a stabilized 3-isothiazolone reaction product containing a ring-stabilizing amount of a stabilizing soluble nitrate salt and at least one biologically active 3-isothiazolone of the formula < IMG > wherein R and R' are independently selected from hydrogen, halogen or an alkyl group of 1 to 4 carbon atoms; Y is an alkyl group of 1 to 8 carbon atoms, a cycloalkyl group of 5 or 6 carbon atoms, an aralkyl group of up to 8 carbon atoms, or an aryl or substituted aryl group of 6 carbon atoms, said 3-isothiazolone reaction product containing less than 100 parts of a nitrosamine of the formula < IMG > and its precursor YNHCH2CH2CONHY, wherein Y is as defined above, for about each 150,000 parts of biologically active 3-isothiazolone.