IN VITRO TESTING METHOD FOR THE DIAGNOSIS OF MALIGNANT TUMOURS

An in vitro testing method for the diagnosis of malignant tumours, preferably human tumours, comprising determining the mobility variation of cellular blood components contacted with a migration inhibition factor (MIF), wherein the MIF is secreted from lymphocytes being sensisized against tumour tis...

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Bibliographic Details
Main Author DOUWES, FRIEDRICH
Format Patent
LanguageEnglish
French
Published 10.08.1982
Subjects
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
SURGERY
TESTING
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Summary:An in vitro testing method for the diagnosis of malignant tumours, preferably human tumours, comprising determining the mobility variation of cellular blood components contacted with a migration inhibition factor (MIF), wherein the MIF is secreted from lymphocytes being sensisized against tumour tissue, whereby subjecting, as said cellular blood components, the lymphocytes as a part of a leucocyte suspension to be examined prior to a migration inhibition test. The lymphocytes are contacted with an antigen capable of stimulating them to produce MIF. The leucocyte migration is inhibited and fixed after a predetermined period of time. The leucocytes migrate in a capillary intermediate layer having a thickness of from 1 to 20 microns and being at least partially filled with liquid. Said intermediate layer is formed between a glass surface and an agar layer. The invention further refers to the construction and preparation of a testing plate or dish.
Bibliography:Application Number: CA19780317809