OXIME ETHERS AND PROCESS FOR THE PREPARATION THEREOF

Novel oxime others of formula I /I/ and their optical isomers, salts and quaternary ammonium derivatives, wherein R stands for a phenyl group which may be substituted by a halogen atom or by one or more C1-C4 alkoxy, hydroxyl, nitro or di/C1-C3 alkyl/amino groups; R1 and R2 denote each a hydrogen at...

Full description

Saved in:
Bibliographic Details
Main Authors KOSOCZKY, IBOLYA, PETOECZ, LUJZA E, GRASSER, KATALIN, SZIRT, ENIKO (NEE KISZELLY), BUDAI, ZOLTAN, MEZEI, TIBOR, LAY, ARANKA (NEE KONYA)
Format Patent
LanguageEnglish
French
Published 05.02.1980
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Novel oxime others of formula I /I/ and their optical isomers, salts and quaternary ammonium derivatives, wherein R stands for a phenyl group which may be substituted by a halogen atom or by one or more C1-C4 alkoxy, hydroxyl, nitro or di/C1-C3 alkyl/amino groups; R1 and R2 denote each a hydrogen atom or together a valence bond; A denotes a C2-C4 straight or branched-chain alkylene group; B denotes an amino or a di/C1-4 alkyl/-amino group or a group of general formula VII /VII/ wherein R3 and R4 denote together a C4-C7 alkylene chain which may contain also a further oxygen or nitrogen heteroatom and the latter may carry also a C1-C3 alkyl or a benzyl substituent; and n denotes an integer from 3 to 10. The new compounds according to the invention possess valuable therapeutic effects. Thus they show local analgesic, spasmolytic, nicotine-lethality inhibiting, tetrabenazine -antagonistic and tetracer-spasm inhibiting effects.
Bibliography:Application Number: CA19760245043