processo para a fabricação de moduladores de regulador de condutância de transmembrana de fibrose cística

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.

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Bibliographic Details
Main Authors MARTIN TRUDEAU, GREGOR ZLOKARNIK, FREDERICK F. VAN GOOR, PETER D. J. GROOTENHUIS, STEFANIE ROEPER, JOHN DEMATTEI, BRIAN R. KRUEGER, BOBBIANNA NEUBERT-LANGILLE, MARTYN C. BOTFIELD, ADAM R. LOOKER, DAHRIKA MILFRED LAO YAP, MICHAEL P. RYAN
Format Patent
LanguagePortuguese
Published 05.07.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.
Bibliography:Application Number: BR2010PI11506