composicoes de peptideos profarmacos de alta penetracao e compostos relacionados a peptideos
A high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit are provided. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide o...
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Main Authors | , , , , |
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Format | Patent |
Language | Portuguese |
Published |
15.03.2016
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Subjects | |
Online Access | Get full text |
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Summary: | A high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit are provided. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide or the peptide-related compound. The transportational unit comprises protonatable amine group. The linker comprises chemical bond that is capable of being cleaved after the composition penetrates across a biological barrier. |
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Bibliography: | Application Number: BR2010PI11439 |