Nanopartícula, composição, métodos para a produção das nanopartículas e de uso, e, uso de nanopartículas

Nanoparticles (10) functionalized with at least one zwitterionic moiety, and compositions comprising said nanoparticles are provided. The nanoparticles (10) have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle (10) compr...

Full description

Saved in:
Bibliographic Details
Main Authors ROBERT EDGAR COLBORN, MICHAEL ERNEST MARINO, MATTHEW DAVID BUTTS, ANDREW SOLIZ TORRES, BRIAN C. BALES, BRUCE ALLAN HAY, AMIT KULKARNI, PETER JOHN BONITATIBUS
Format Patent
LanguagePortuguese
Published 28.07.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:Nanoparticles (10) functionalized with at least one zwitterionic moiety, and compositions comprising said nanoparticles are provided. The nanoparticles (10) have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle (10) comprises a core (20), having a core surface (30) essentially free of silica, and a shell (40) attached to the core surface (30). The shell (40) comprises at least one silane- functionalized zwitterionic moiety. Further, methods of making said nanoparticles and methods of their use as diagnostic agents are provided.
Bibliography:Application Number: BR2009PI23859