derivado de fenilacetamida

[Problems] To provide a compound which is useful as a GK activator. [Means for Solving Problems] The present inventors have conducted extensive studies on a phenylacetamide derivative, and as a result, have confirmed that a phenylacetamide derivative having sulfonyl group and cycloalkyl group on the...

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Main Authors KEISUKE MAKI, MASAHIKO HAYAKAWA, MITSUAKI OKUMURA, AKIRA KANAI, YOSHIYUKI KIDO, TAKAHIRO NIGAWARA, NOBUAKI AMINO
Format Patent
LanguagePortuguese
Published 03.11.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:[Problems] To provide a compound which is useful as a GK activator. [Means for Solving Problems] The present inventors have conducted extensive studies on a phenylacetamide derivative, and as a result, have confirmed that a phenylacetamide derivative having sulfonyl group and cycloalkyl group on the phenyl group and having heteroaryl group on the nitrogen atom in the amide has an excellent GK activation action, thereby completing the present invention. The compound of the present invention is useful as an agent for treating diabetes, in particular, type II diabetes, since it has an excellent GK activation action.
Bibliography:Application Number: BR2009PI06888