TITULAÇÕES DE POLIPEPTÍDEO DO FATOR VIII EM CULTURAS DE CÉLULAS

The invention relates to a method for the production of a Factor VIII polypeptide, the method comprising the steps of a) culturing a mammalian cell expressing a Factor VIII polypeptide under conditions for expression of said Factor VIII polypeptide, said culturing conditions involving a cell culture...

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Bibliographic Details
Main Authors GERT BOLT, LAUST BRUUN JOHNSEN, THOMAS DOCK STEENSTRUP, IDA HILDEN
Format Patent
LanguagePortuguese
Published 29.10.2014
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The invention relates to a method for the production of a Factor VIII polypeptide, the method comprising the steps of a) culturing a mammalian cell expressing a Factor VIII polypeptide under conditions for expression of said Factor VIII polypeptide, said culturing conditions involving a cell culture medium comprising a C2-domain ligand, and b) isolating the expressed Factor VIII polypeptide from the mammalian cell by suitable means.
Bibliography:Application Number: BR2008PI11177