DERIVADOS DE 6-OXO-6,7-DI-HIDRO-5H-DIBENZO[B,D]AZEPIN-7-ILA

The invention relates to 6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl derivatives of formula I wherein R1, R2 and R3 are as defined herein. The compounds are gamma-secretase inhibitors useful in the treatment of Alzheimer's disease or common cancer, including, but not limited to, cervical carci...

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Bibliographic Details
Main Authors ALEXANDER FLOHR, WOLFGANG WOSTL, ROLAND JAKOB-ROETNE
Format Patent
LanguagePortuguese
Published 20.05.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to 6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl derivatives of formula I wherein R1, R2 and R3 are as defined herein. The compounds are gamma-secretase inhibitors useful in the treatment of Alzheimer's disease or common cancer, including, but not limited to, cervical carcinomas and breast carcinomas and malignancies of the hematopoietic system.
Bibliography:Application Number: BR2008PI07341