PROCESSO DE SÍNTESE DA N-[3-[(2-METÓXI FENIL) SULFANIL] -2-METIL PROPIL]- 3,4-DI-HIDRO -2H-1,5-BENZOXATIEPIN -3-AMINA
Preparation of N-[3-[(2-methoxyphenyl)sulfanyl]-2-methylpropyl]-3,4-dihydro-2H-1,5-benzoxathiepin-3-amine (I) comprises condensation of 7,8-dihydro-6H-5-oxa-9-thia-benzocyclohepten-7-ylamine compound (II) and 5-methoxy-6-(2-methyl-butylsulfanyl)-cyclohexa-1,3-diene compound (III). Preparation of N-[...
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Main Authors | , , |
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Format | Patent |
Language | Portuguese |
Published |
07.01.2014
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Subjects | |
Online Access | Get full text |
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Summary: | Preparation of N-[3-[(2-methoxyphenyl)sulfanyl]-2-methylpropyl]-3,4-dihydro-2H-1,5-benzoxathiepin-3-amine (I) comprises condensation of 7,8-dihydro-6H-5-oxa-9-thia-benzocyclohepten-7-ylamine compound (II) and 5-methoxy-6-(2-methyl-butylsulfanyl)-cyclohexa-1,3-diene compound (III). Preparation of N-[3-[(2-methoxyphenyl)sulfanyl]-2-methylpropyl]-3,4-dihydro-2H-1,5-benzoxathiepin-3-amine (I) comprises condensation of intermediate of 7,8-dihydro-6H-5-oxa-9-thia-benzocyclohepten-7-ylamine compound (II) and 5-methoxy-6-(2-methyl-butylsulfanyl)-cyclohexa-1,3-diene compound of formula (III). R : methyl group, preferably 4-methylphenyl. An independent claim is included for the new intermediate compound (III). [Image] ACTIVITY : Antianginal; Cardiant. MECHANISM OF ACTION : None given. No biological data given. |
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Bibliography: | Application Number: BR2007PI18702 |