composto (-) -halofenato, composição farmacêutica, métodos para produzir um composto, para enriquecer enantiomericante um composto, para evitar ou tratar uma condição, e para a preparação de uma composição farmacêutica, e, composição

The present invention provides crystalline solid and amorphous forms of (−)-halofenate. The crystalline solid forms may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of conditions associated with blood lipid deposition in a mammal,...

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Bibliographic Details
Main Authors Edward D. Daugs, DAVID H. LOUKS, ERIC J. HAGEN, JASON A. HANKO
Format Patent
LanguagePortuguese
Published 31.01.2017
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention provides crystalline solid and amorphous forms of (−)-halofenate. The crystalline solid forms may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of conditions associated with blood lipid deposition in a mammal, particularly those diseases related to Type 2 diabetes and hyperlipidemia. The invention also relates to a method for preventing or treating Type 2 diabetes and hyperlipidemia in a mammal comprising the step of administering a therapeutically effective amount of crystalline solid and amorphous forms of (−)-halofenate.
Bibliography:Application Number: BR2006PI10782