película de gel termorreversível homogênea, processo para fabricar as películas de gel, cápsulas moles, processo para fabricar as cápsulas moles, e, forma sólida

• Main Authors: Christopher J. Sewall, Peter J. Riley, William R. Blakemore, Arthur D. Ballard, James J. Modliszewski
• Format: Patent
• Language: Portuguese
• Published: 06.02.2018
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; FISHING; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING; PERFORMING OPERATIONS; PEST REPELLANTS OR ATTRACTANTS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; TRANSPORTING; TRAPPING

"película de gel termorreversível homogênea processo para fabricar as películas de gel, cápsulas moles, processo para fabricar as cápsulas moles, e, forma solida". a presente invenção está direcionada a uma película de gel termorreversível homogênea que compreende uma quantidade formadora de pelicula de capa-2 carragenano e opcionalmente pelo menos um de um plastificante, um segundo formador de película, um agente encorpante e um agente controlador de ph; e processos para a sua preparação. a presente invenção também está direcionada às cápsulas moles e formas sólidas contendo a película de gel, assim como aos processos para a sua preparação. Abstract of the Disclosure The present invention is directed to a process for making homogeneous, thermoreversible gel films comprising the steps of: (i) heating, hydrating, mixing, solubilizing, and, optionally, de-aerating a high solids, low moisture film forming composition in an apparatus providing sufficient shear, temperature and residence time to form a homogeneous molten composition, wherein the temperature is at or above the solubilizing temperature of said composition; (ii) feeding the molten composition into at least one of a mixer, pump or devolatilizer; and (iii) cooling the homogeneous molten composition at or below its gelling temperature to form said gel films. The present invention is also directed to various products made from such films, such as the gel films themselves, soft capsules, solid dosage forms and delivery systems.