n-hidróxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]-amino]metil]fenil]-2e-2-propenamida, composição farmacêutica compreendendo o mesmo e uso

"inibidores da desacetilase". a presente invenção fornece compostos de hidroxamato que são inibidores das desacetilases. os compostos são adequados para composições farmacêuticas que possuem propriedades antiproliferativas. The present invention provides hydroxamate compounds of formula I:...

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Bibliographic Details
Main Authors Michael A. Green, Lidia Sambucetti, Richard William Versace, Kenneth Walter Bair, Sushil Kumar Sharma, Lawrence B. Perez, Stacy W. Remiszewski
Format Patent
LanguagePortuguese
Published 25.05.2021
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:"inibidores da desacetilase". a presente invenção fornece compostos de hidroxamato que são inibidores das desacetilases. os compostos são adequados para composições farmacêuticas que possuem propriedades antiproliferativas. The present invention provides hydroxamate compounds of formula I: which are deacetylase inhibitors. The compounds are suitable for pharmaceutical compositions having anti-proliferative properties.
Bibliography:Application Number: BR20010113669