peptÍdios antagonistas de inibidores de tgf-beta1 e seu uso

Antagonistic synthetic peptides, obtained from TGF beta 1 or from its receptors in the organism, that can be used in the manufacture, both on their own, as well as the gene sequences that encode them and the recombinant systems that express them, in the manufacture of compositions for use in the tre...

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Main Authors JUAN JOSE LASARTE SAGASTIBELZA, FRANCISCO BORRAS CUESTA, JESUS PRIETO VALTUENA, IGNACIO JOSE EZQUERRO SAENZ
Format Patent
LanguagePortuguese
Published 26.07.2011
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Antagonistic synthetic peptides, obtained from TGF beta 1 or from its receptors in the organism, that can be used in the manufacture, both on their own, as well as the gene sequences that encode them and the recombinant systems that express them, in the manufacture of compositions for use in the treatment of liver diseases and more concretely in cases of fibrosis. The said compositions can optionally include mimotopes of the said active peptides.
Bibliography:Application Number: BR19999915604