Vesículas com liberação controlada de ativos
A multivesicular liposome composition containing at least one acid other than a hydrohalic acid and at least one biologically active substance, the vesicles having defined size distribution, adjustable average size, internal chamber size and number, provides a controlled release rate of the biologic...
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Main Author | |
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Format | Patent |
Language | Portuguese |
Published |
12.08.1997
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | A multivesicular liposome composition containing at least one acid other than a hydrohalic acid and at least one biologically active substance, the vesicles having defined size distribution, adjustable average size, internal chamber size and number, provides a controlled release rate of the biologically active substance from the composition. A process for making the composition features addition of a non-hydrohalic acid effective to sustain and control the rate of release of an encapsulated biologically active substance from the vesicles at therapeutic levels in vivo. |
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Bibliography: | Application Number: BR19949408072 |