Formas cristalinas de moduladores de cftr

formas cristalinas de moduladores de cftr. são divulgadas formas cristalinas do composto i: fórmula (i), sais farmaceuticamente aceitáveis destas, e solvatos e hidratos das mesmas. as composições farmacêuticas que as compreendem, métodos de tratamento da fibrose cística que as utilizam e métodos par...

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Main Authors ZHOU JINGLAN, PIERRE FABRICE, LI JICONG, MCCARTNEY JASON, SHI YI, CARL L. ZWICKER, PARASELLI PRASUNA, MEDEK ALES, SARA SABINA HADIDA RUAH, CLEVELAND THOMAS, SHRESTHA MUNA, SARA E. SWIFT, ZHANG BEILI, MARK THOMAS MILLER, TIMOTHY RICHARD COON, LU JENNIFER, COREY DON ANDERSON, KEVIN J. GAGNON, GROOTENHUIS PETER, FRIEMAN BRYAN, WALDO MICHAEL, JEREMY J. CLEMENS
Format Patent
LanguagePortuguese
Published 03.05.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:formas cristalinas de moduladores de cftr. são divulgadas formas cristalinas do composto i: fórmula (i), sais farmaceuticamente aceitáveis destas, e solvatos e hidratos das mesmas. as composições farmacêuticas que as compreendem, métodos de tratamento da fibrose cística que as utilizam e métodos para produzi-las também são divulgados. Crystalline forms of Compound I:pharmaceutically acceptable salts thereof, and solvates and hydrates thereof are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
Bibliography:Application Number: BR20221102605