composto, composição farmacêutica, e, método para tratamento de um câncer

a invenção refere-se a compostos da fórmula (i), em que r1, r2, r3, r4, r5 e são conforme definido na descrição. The invention relates to compounds of formula (I):wherein R1;R2, R3, R4, R5andare as defined in the description. The compounds of formula (I) are inhibitors of the YAP/TAZ-TEAD interactio...

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Bibliographic Details
Main Authors CHRISTIAN MONTALBETTI, MARTINE BARTH, ANNE SOUDE, CHRISTINE MASSARDIER, SYLVIE CONTAL, JEAN-LOUIS JUNIEN
Format Patent
LanguagePortuguese
Published 06.07.2021
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:a invenção refere-se a compostos da fórmula (i), em que r1, r2, r3, r4, r5 e são conforme definido na descrição. The invention relates to compounds of formula (I):wherein R1;R2, R3, R4, R5andare as defined in the description. The compounds of formula (I) are inhibitors of the YAP/TAZ-TEAD interaction and thus useful in the treatment of cancer.
Bibliography:Application Number: BR20211106229