células t com receptor de antígeno coestimulador quimérico direcionadas à il13ra2

Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes IL-13 or a variant thereof that binds interleukin-13Ra2 (IL13Ra2), a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.

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Bibliographic Details
Main Authors CHRISTINE E. BROWN, STEPHEN J. FORMAN
Format Patent
LanguagePortuguese
Published 26.06.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes IL-13 or a variant thereof that binds interleukin-13Ra2 (IL13Ra2), a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.
Bibliography:Application Number: BR20171105631