dispersão sólida, formulação sólida, método de preparo de uma dispersão sólida, preparação farmacêutica e uso de uma dispersão sólida

The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.

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Bibliographic Details
Main Authors STEVE LOMUSCIO, HARPREET K. SANDHU, NAVNIT HARGOVINDAS SHAH, MICHAEL ALLEN MATCHETT, HUA MA, YU-E ZHANG
Format Patent
LanguagePortuguese
Published 19.06.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.
Bibliography:Application Number: BR20151115758