sistema, método para capturar o alvo celular, lisado celular e ligante de captura

The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally pres...

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Bibliographic Details
Main Authors CAROLYN W. HITKO, ROBIN HURST, THOMAS KIRKLAND, KEITH WOOD, PONCHO MEISENHEIMER, DIETER KLAUBERT, NIDHI NATH, MARJETA URH, RACHEL F. OHANA, PAUL OTTO, HARRY TETSUO UYEDA
Format Patent
LanguagePortuguese
Published 26.09.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture fusions), surfaces (e.g., displaying, capture ligands, capture proteins, or capture fusions), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.
Bibliography:Application Number: BR20151113715