método para a produção de um antígeno viral derivado de vírus envelopado, e, uso de um método para a fabricação de uma preparação de vacina contendo o antígeno viral

The present invention belongs to the field of pharmaceutical industry and relates to a method for the production of viral antigen derived from enveloped virus, comprising the steps of providing a fluid comprising enveloped virus, clarifying the fluid comprising said enveloped virus, reducing the vol...

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Bibliographic Details
Main Authors RON VAN'T HOF, YIDING WANG, GEERTJE JACOBA VAN ROOIJ, SABAH SHAKER, JO THUS, YI-QING CUI
Format Patent
LanguagePortuguese
Published 21.02.2017
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Summary:The present invention belongs to the field of pharmaceutical industry and relates to a method for the production of viral antigen derived from enveloped virus, comprising the steps of providing a fluid comprising enveloped virus, clarifying the fluid comprising said enveloped virus, reducing the volume of the obtained liquid harvest, solubilizing the enveloped virus, and purifying viral antigen. The present invention further refers to the use of said method for the production of a vaccine preparation.
Bibliography:Application Number: BR20141101049