inibidores de nampt e rock

Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are isoindoline carboxa...

Full description

Saved in:
Bibliographic Details
Main Authors MARINA A. PLIUSHCHEV, ANIL VASUDEVAN, RICHARD F. CLARK, TODD .M HANSEN, OMAR J. SHAH, CHRIS TSE, HOWARD R. HEYMAN, MICHAEL L. CURTIN, MICHAEL MICHAELIDES, HELMUT MACK, RAMZI SWEIS, BRYAN K. SORENSEN, KEVIN R. WOLLER
Format Patent
LanguagePortuguese
Published 24.09.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of treating diseases during which ROCK is expressed.
Bibliography:Application Number: BR20131112078