Método não terapêutico de desinfecção e composição para tratar uma superfície contaminada com uma proteína prion PrPSc ou um substituto da mesma

The invention relates to a methods and compositions for treating a surface, suspension or solution contaminated with a PrP sc prion protein or a surrogate thereof. The methods and compositions employ a combination of one or more enzymes effective to cleave a prion protein to fragments having a non-i...

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Bibliographic Details
Main Authors STEVEN KRIRTZLER, MICHAEL ZALUNARDO, ALEX SAVA
Format Patent
LanguagePortuguese
Published 16.09.2014
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BEER
BIOCHEMISTRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
DIAGNOSIS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
ENZYMOLOGY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
IDENTIFICATION
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
SPIRITS
SURGERY
TRAPPING
VINEGAR
WINE
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Summary:The invention relates to a methods and compositions for treating a surface, suspension or solution contaminated with a PrP sc prion protein or a surrogate thereof. The methods and compositions employ a combination of one or more enzymes effective to cleave a prion protein to fragments having a non-infective molecular weight, and one or more agents selected to favour conformational unfolding of the PrP sc prion protein while not denaturing the one or more enzymes.
Bibliography:Application Number: BR20020207305